|Sample Requirement||Turnaround Time|
|Serum||Same working day|
This assay is valuable as an assessment of colostral transfer of immunity to the newborn foal. In a normal equine pregnancy, there is no transplacental transfer of IgG before birth and foals are born essentially agammaglobulinaemic. During the last few months of gestation, mares concentrate IgG in their colostrum. Foals intestines are capable of absorbing IgG for their first 12-18 hours of life.
We measure IgG by an immunoturbidimetric method. This method is more reliable than most 'foal-side' tests currently available, especially in the critical lower range (0-4 g/l).
Serum samples should be taken from foals on the second day of life when IgG levels should ideally be >8 g/l. Levels <4 g/l suggest failure and 4-8 g/l suggest partial failure of colostral immunity, and prophylactic measures may be indicated, dependent on the result and clinical setting/risk factors.
In cases where plasma transfusion is indicated we recommend the use of commercial hyperimmune plasma. If non-commercial donor plasma is being considered, we can run compatibility tests between donor serum and recipient red cells.
Measuring IgG in colostrum can be used to predict failure of passive transfer in the foal. Colostral IgG is measured semi-quantitatively immediately after parturition, using a refractometer (Colostrometer). If readings suggest an IgG level of less than 45g/l, the foal should be considered for donor colostrum supplementation.
|Neonatal Thoroughbred Foals (24-48hrs old)||6.9-18.6|